Serum Ferritin 1. Deloche C; Bastien P; Chadoutaud S; Galan P; Bertrais S; Hercberg S; de Lacharrière O; “Low Iron Stores: A Risk Factor for Excessive Hair Loss in Non-Menopausal Women,” European journal of dermatology: EJD (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/17951130/
2. Kantor J; Kessler LJ; Brooks DG; Cotsarelis G; “Decreased Serum Ferritin Is Associated with Alopecia in Women,” The Journal of investigative dermatology (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/14708596/ Iron deficiency is the world’s most common nutritional deficiency and experts believe as much as 30% of women less than 50 years old suffer from low iron. Iron deficiency is also the leading cause of nutrition-based hair loss in women.
Vitamin D 3. Saini K; Mysore V; “Role of Vitamin D in Hair Loss: A Short Review,” Journal of cosmetic dermatology (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/34553483/ Most studies show an inverse relationship between serum vitamin D levels and non-scarring alopecias such as telogen effluvium, androgenetic alopecia, alopecia areata, and trichotillomania.
Ketoconazole 4. Ahmed El-Garf, Mohamed Mohie, and Eman Salah, “Trichogenic Effect of Topical Ketoconazole versus Minoxidil 2% in Female Pattern Hair Loss: A Clinical and TRICHOSCOPIC Evaluation – Biomedical Dermatology,” BioMed Central (BioMed Central, December 5, 2019. https://biomeddermatol.biomedcentral.com/articles/10.1186/s41702-019-0046-y Studies show that in addition to anti-fungal and anti-inflammatory properties, ketoconazole can also increase hair density and thickness when compared to a placebo. Experts believe it reduces underlying hormone activity that can block new hair growth.
5% minoxidil 5. Bergfeld W; Washenik K; Callender V; Zhang P; Quiza C; Doshi U; Blume-Peytavi U; “A Phase III, Multicenter, Parallel-Design Clinical Trial to Compare the Efficacy and Safety of 5% Minoxidil Foam versus Vehicle in Women with Female Pattern Hair Loss,” Journal of drugs in dermatology: JDD (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/27391639/ In a recent study, 80% of women using 5% minoxidil daily showed reduced shedding, and half of those showed more hair in just 24 weeks. The minoxidil responders showed 4.5x as much new hair growth and a 48% increase in hair diameter vs. those using a placebo.
Strength of LLLT Dosage 6. Hamblin MR; “Photobiomodulation for the Management of Alopecia: Mechanisms of Action, Patient Selection, and Perspectives,” Clinical, cosmetic and investigational dermatology (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/31686888/
7. Gupta AK; Bamimore MA; “Factors Influencing the Effect of Photobiomodulation in the Treatment of Androgenetic Alopecia: A Systematic Review and Analyses of Summary-Level Data,” Dermatologic therapy (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/32790116/ A recent study showed that the stronger dose used in prescription-strength LaserCap, produced superior results when compared to units with lower power.
Pulsing Laser Light 8. Javad T Hashmi et al., “Effect of Pulsing in Low-Level Light Therapy,” Lasers in surgery and medicine (U.S. National Library of Medicine, August 2010). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933784/ A recent study showed that pulsed light applications in the use of low-level laser therapy generated stronger responses when compared to similar strength constant light.
PRP Regimens 9. Hausauer AK; Jones DH; “Evaluating the Efficacy of Different Platelet-Rich Plasma Regimens for Management of Androgenetic Alopecia: A Single-Center, Blinded, Randomized Clinical Trial,” Dermatologic surgery: official publication for American Society for Dermatologic Surgery [et al.] (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/30141776/ A clinical trial published in May of 2018 showed that 80% of participants with mild to moderate hair loss, when following the exact sequencing of treatments that are used by Thairapy, saw as much as 30% higher hair counts at six months.
PRP Concentration for AGA 10. Sasaki GH; “The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) on Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study,” Aesthetic surgery journal (U.S. National Library of Medicine), accessed April 19, 2022. https://pubmed.ncbi.nlm.nih.gov/34050738/ A small study published in May of 2021 showed that increasing the concentration of platelets in the PRP solution to twice the earlier standard, delivered higher follicle diameter measurement as well as an increase in terminal hair density.
